cosmeBun

In-silico makeup toxicity & dermal-response predictor

Ingredient input

INCI / CAS bulk-aware lookup

Concentration precision down to 0.001%. Paste a full deck to bulk-import.

Formula deck

8 ingredients · total 83.60%

Aqua (Water)

otherCAS 7732-18-5
%

Glycerin

humectantCAS 56-81-5
%

Niacinamide

activeCAS 98-92-0
%

Retinol

activeCAS 68-26-8
%

Phenoxyethanol

preservativeCAS 122-99-6
%

Parfum (Fragrance)

fragrance
%

Cetearyl Alcohol

emulsifier
%

Squalane

emollientCAS 111-01-3
%

Global Hazard Index

Cumulative T_total · scaled 0–100

39GHI

Borderline — review flagged components

T_total combines weighted baseline toxicity (α) and non-linear synergy multipliers (β_ij) across the current deck.

Low
Mid
High

Compliance

Regional ban-list cross-reference

  • EU Cosmetics Reg. (Annex II)

    No banned substances detected

    Pass

  • US FDA MoCRA

    No banned substances detected

    Pass

  • China CSAR

    No banned substances detected

    Pass

Granular skin biomarker breakdown

Epidermal absorption response

Dermal Irritation / Erythema

35.6

Ocular Hazard Profile

30.4

Sensitization Potential

34.2

Comedogenicity

14.1

Epidermal layer absorption

Predicted depth penetration by ingredient

Niacinamide

Cetearyl Alcohol

Phenoxyethanol

Parfum (Fragrance)

Squalane